Collaborations & Alliances

Debiopharm, Merck KGaA, Pfizer in Clinical Collaboration

Joint effort to assess safety and efficacy of Debio 1143 with avelumab in lung cancer

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By: Kristin Brooks

Managing Editor, Contract Pharma

Debiopharm has entered into a collaboration with Merck KGaA and Pfizer to evaluate Debio 1143, an oral, small molecule inhibitor of IAPs (Inhibitor of Apoptosis Proteins), in combination with avelumab, an investigational fully human anti-PD-L1 IgG1 monoclonal antibody, in advanced or metastatic Non-Small Cell Lung Cancer (NSCLC).   Debio 1143 is currently in Phase II development for head and neck and ovarian cancer. Avelumab is under investigation across a broad range of tumor types by Merck K...

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